Sterilizer ADV – the ideal unit for testing and R&D

sterilizer ADV

The sterilizer ADV exhibited at Achema 2012 in Frankfurt, Germany, unites equipment sterilization via vacuum process with product sterilization via steam/air mixture process. The combination of these two processes offers highest flexibility: The sterilizer can be used for almost any product and is also suited for the development of new products.The flexible recipe editor enables quick and individual adjusting of parameters. The universally applicable system has been developed for research institutes and laboratories, as well as for the pharmaceutical and biotechnical industries. It sterilizes blister-packaged goods and machine parts, contact lenses, blood bag systems and nested glass syringes, ampoules and vials, as well as glass or plastic bottles.


The steam/air mixture process is used for the sterilization of liquids in open, semi-closed and closed containers, and is characterized by dry removal. Ventilators circulate the steam/air mixture inside the chamber and achieve a homogenous temperature distribution. Internal heat exchangers circulate sterile air for cooling. During the process, counter-pressure is maintained in the chamber to prevent damages to the product. At the end of the cycle, the load can be removed in a dry condition.


The vacuum process is especially suited for sterilizing machine parts, filters, rubber stoppers and equipment. Rigid and porous loads, as well as machine cavities can be sterilized using the steam/vacuum process. The pre-vacuum steps ensure the elimination of air from the chamber. Heating and sterilizing is achieved by saturated steam. Depending on the load, this step is followed either by vacuum drying or jacket cooling.


Schoeller-Bleckmann Medizintechnik (SBM), located in Ternitz, Austria, is a subsidiary of Bosch Packaging Technology and draws on over 35 years of experience in the pharmaceutical industry. The autoclave sterilization portfolio includes standard modules as well as customized solutions.




Isa Alkan

Sales and Marketing Director

phone: +43 2630 312 204


2 Responses

  1. gh.ali says:

    Hello Dear master
    I’m working in the company that produces medical equipment (consortium of Iranian dialysis).
    The company’s products include Blood bag, Hemodialysis solution, dialysis treatment and . . . .
    The company is in the city of Tehran, Iran.
    Some of these products are sterilized by ethylene oxide and the other(Blood bag) by air-steam. Blood bag system is a disposable bio-medical device used for collection, storage, transportation and transfusion of human blood and blood components. The system consists of a single or multiple bags connected with tubes, needle, needle cover, clamp etc. The Blood Bags are made of plastic material which is compatible with blood.
    The blood bags are manufactured from bio-compatible PVC, compounded with suitable additives. The formulation is used for making sheets, tubes by extrusion and other components like transfusion ports, clamps, needle cover etc.
    The anticoagulant constituents(CPD,CPDA) are premixed and solution is prepared in pyrogenic free distilled water. All the operations are done in conformity to GMP. The anti-coagulant solution is filled in the blood bags.
    It is advantageous to first fill the package (polypropylene) with the content to be sterilized, close the package and then sterilize the package with the content. Polypropylene film thickness is (120) Micron.
    Steam sterilization involves the use of steam-air under pressure(3 bar) and temperature(120 ͦᶜ) in autoclave. The length of time that the packages are in this condition(50 minutes).Of course, I believe due to the low permeability(0.70 grams on square centimeters in the last 24 hours) Polypropylene film this is a long time, and Should be reduced (About 35 minutes).
    The main problem with the package of Blood bag is that during the sterilization steam penetrates through the package wall into the package (To Sterilize the content inside the package). After cooling down(40 ͦᶜ)the Steam is present as water vapor and drops inside the package. This moisture is removed during drying process with 18 hours. ( this is a long time).Process of drying at atmospheric pressure and temperatures ( 60 ͦᶜ ) done.
    We’re looking for a way to reduce the time of drying process(Approximately 2 hours).
    Can you help me?
    thank you very much.

    Best regards,

    • Stefanie Krauß Stefanie Krauß says:

      Dear Ghorban Ali,

      we are very well aware of that problem to have condensate in the bags after sterilization. I don’t know what sterilizer you are using at the moment but an optimized and strong circulation of steam/air improves that a lot – for that strong radial fans are needed. The main problem we see occur during fast heating with steam and cold bags, so the only way we offer to customer is to preheat the product in the close chamber with hot air only to 60-70°C before starting heating and sterilization with steam, that normally increases the cycle time for about 30 minutes and you have a dry product at the end. The alternative is closed drying tunnels after sterilization that normally need a lot of space and are expensive.

      I hope the answer does help you, please let us know if we can be of further help.
      Your contact person is Isa Alkan

      Best regards,
      Stefanie Krauß

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